How to Write a Research Proposal
A research proposal explains what you will study, why it matters, how you will do it, what it will cost and how you will manage risks. A good proposal is concise, logically consistent and shows that you have thought through feasibility and ethics.
Structure and what each part must answer
| Section | Must answer |
|---|---|
| Title | What is the study and design? |
| Background and rationale | What is known, what is the gap, why does it matter? |
| Question and objectives | What exactly will be answered? |
| Methods | Design, participants, outcomes, data, analysis, bias control |
| Ethics | How are participants protected? Approvals needed? |
| Timeline | Who does what and when? |
| Budget and resources | What is needed? |
| Expected outputs | Papers, presentations, data sharing |
| References | Key sources, accurately cited |
Writing steps
- Start with the question and objectives.
- Write the methods as if explaining them to an expert reviewer.
- Justify the sample size or explain why none is calculated.
- Add risks and mitigation (recruitment, missing data).
- Draft background last, to match what the methods need.
- Ask a mentor to review for logic and feasibility.
Illustrative example
Invented for teaching. A weak methods paragraph: "We will study patients with diabetes." Stronger: "We will include adults aged 18 or older with type 2 diabetes attending the outpatient clinic from January to June 2027, excluding pregnancy. The primary outcome is HbA1c at 6 months, abstracted from clinical records, analysed with a linear model adjusted for baseline HbA1c."
Common pitfalls
- A background that reads like a review and ignores the question.
- Methods that do not match objectives.
- Unrealistic timelines.
Key takeaways
- Make the logic visible: gap → question → methods → analysis.
- Use MRN's free research proposal template as a scaffold.
References and further reading
- Chan AW, Tetzlaff JM, Altman DG, et al. SPIRIT 2013 statement: defining standard protocol items for clinical trials. Ann Intern Med. 2013;158(3):200-207. doi:10.7326/0003-4819-158-3-201301080-00007
- Hulley SB, Cummings SR, Browner WS, Grady D, Newman TB. Designing Clinical Research. 4th ed. Lippincott Williams & Wilkins; 2013. Link
- International Committee of Medical Journal Editors (ICMJE). Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals. Link
Related reading
This page is general educational information about research methods. It is not medical, legal or regulatory advice; follow your institution's ethics board and your target journal's instructions.
