BIOSTATISTICS AND DATA

Parametric vs Nonparametric Tests

Guide · 1 min read · Last updated 2026-10-31

Parametric tests assume the data follow a particular distribution (often normal) and use parameters such as the mean and SD; nonparametric tests make fewer distributional assumptions, usually working with ranks. Choose by the data type, distribution, sample size and design, and decide the plan in advance.

Common pairs

SituationParametricNonparametric
Compare two independent groupsIndependent t-testMann-Whitney U (Wilcoxon rank-sum)
Compare two paired measurementsPaired t-testWilcoxon signed-rank test
Compare 3 or more groupsOne-way ANOVAKruskal-Wallis test
Correlation between two numerical variablesPearson correlationSpearman rank correlation

Trade-offs

  • Parametric tests are more efficient when assumptions hold.
  • Nonparametric tests are more robust to skew and outliers and suit ordinal data, but may have less power when data are truly normal and they test a different hypothesis (about ranks or distributions, not strictly means).
  • With large samples, parametric tests are often robust to moderate non-normality because of the central limit theorem, but severe skew or outliers still matter.

How to decide

  1. Identify the data type: ordinal data usually require nonparametric methods.
  2. Look at the distribution (histogram, plots) rather than relying only on a normality test, which is unreliable with very small or very large samples.
  3. Consider transformations (for example log) for skewed data.
  4. Pre-specify the main analysis, and check robustness with the alternative.

Illustrative example

Invented for teaching. Length of stay (days) is highly right-skewed in two groups of 30 patients. The authors plan a Mann-Whitney test and report medians (IQR). They also report a bootstrap confidence interval for the difference in medians, as advised by a statistician.

Common pitfalls

  • Choosing the test after seeing which gives p < 0.05.
  • Using the normality test p-value alone to choose.

Key takeaways

  • Choose a test that fits the data and question; pre-specify it.
  • Report summary statistics that match the test.

References and further reading

  1. Hulley SB, Cummings SR, Browner WS, Grady D, Newman TB. Designing Clinical Research. 4th ed. Lippincott Williams & Wilkins; 2013. Link
  2. Altman DG, Bland JM. Standard deviations and standard errors. BMJ. 2005;331:903. doi:10.1136/bmj.331.7521.903

Related reading

This page is general educational information about research methods. It is not medical, legal or regulatory advice; follow your institution's ethics board and your target journal's instructions.